[카테고리:] 폐질환

대기 오염이 DNA에 해를 끼치지 않고 폐암을 유발하는 방법

생쥐를 대상으로 한 연구에 따르면 종양 성장은 유전적 돌연변이가 아닌 작은 입자로 인한 염증에 의해 유발됩니다. NEWS, 05 April 2023 How air pollution causes lung cancer — without harming DNA Studies in mice suggest that tumour growth is triggered by inflammation caused by tiny particles, rather than genetic mutations. https://www.nature.com/articles/d41586-023-00989-z  Air pollution from vehicles and […]

강력한 경구 항결핵제로서의 천연 제품 유래 세쿼나마이신의 발견

ARTICLE Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents Jidong Zhang, Christine Lair, Christine Roubert, Anna Upton, James C. Sacchettini, Sophie Lagrange, Open AccessPublished:February 23, 2023DOI:https://doi.org/10.1016/j.cell.2023.01.043 https://www.cell.com/cell/fulltext/S0092-8674(23)00102-2 Highlights Structure-based medicinal chemistry leads to an optimized sequanamycin-derived lead molecule, SEQ-9 Sequanamycins are macrolide antibiotics able to overcome inherent Mtb macrolide resistance SEQ-9 is able to adjust its binding mode to […]